Searchable abstracts of presentations at key conferences in endocrinology

ea0023oc4.1 | Oral Communications 4 | BSPED2009

Parahippocampal aberrations in children with GH deficiency: a diffusion tensor imaging study

Webb E A , O'Reilly M , Seunarine K , Clayden J , Dale N , Salt A , Clark C , Dattani M T

Introduction: There is a large body of evidence to suggest that the GH axis plays an important role in brain myelination. However, results from studies in humans with an abnormal GH axis have varied and therefore there remains no consensus as to whether the GH/IGF1 axis plays a significant role in neural development. No previous studies have used diffusion tensor imaging (DTI) a sensitive magnetic resonance imaging (MRI) technique for studying brain white matter tracts, to add...